plasma agp (Proteintech)
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Structured Review
Proteintech
plasma agp
Plasma Agp, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 89 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+agp/FUCA2+Antibody/pmc11967248-74-0-18
Average 94 stars, based on 89 article reviews
Plasma Agp, supplied by Proteintech, used in various techniques. Bioz Stars score: 94/100, based on 89 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/plasma+agp/FUCA2+Antibody/pmc11967248-74-0-18
Average 94 stars, based on 89 article reviews
plasma agp - by Bioz Stars,
2026-09
94/100 stars
Images
1) Product Images from "Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages"
Article Title: Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages
Journal: Cancer Science
doi: 10.1111/cas.70014
Figure Legend Snippet: Mouse experiments using glioma cell lines and spatial analysis of human GBM. (A) Schema of mouse experiment. (B) Survival curve of WT and AGP KO mice after intracranial injection of GL261. (C) CD34 immunostaining of brain tissue from WT and AGP KO mice in the GL261 injection group and control group. (D) Comparison of tumor vascular area between WT and AGP KO mice in the GL261 injection group.
Techniques Used: Injection, Immunostaining, Control, Comparison
Figure Legend Snippet: Expression of PLVAP and AGP in relation to GBM malignancy. (A) Double immunostaining and immunofluorescence showing the expression of Ki67 around PLVAP‐positive vessels. The lower panel shows a comparison of Ki67 positivity around PLVAP‐positive and negative vessels. (B) IHC of PLVAP in normal brain and glioma grades 2–4. (C) Plasma AGP levels in normal adults and human GBM patients. (D) IHC of AGP in normal brain and glioma grades 2–4. (E) AGP leakage around vessels in untreated GBM cases. (F) Comparison of AGP immunostaining before and after Bev treatment. ** p < 0.01, **** p < 0.0001.
Techniques Used: Expressing, Double Immunostaining, Immunofluorescence, Comparison, Clinical Proteomics, Immunostaining
Figure Legend Snippet: Schematic representation of the findings from this study. In GBM, before BBB disruption occurs, PLVAP in the vascular endothelium is negative, Claudin‐5 is positive, and AGP is present only within the blood vessels. Tumor angiogenesis is promoted by VEGF released from tumor cells and GAMs. However, once BBB disruption occurs, the vascular endothelium undergoes abnormal proliferation, PLVAP becomes positive, and Claudin‐5 becomes negative. PLVAP becomes positive. AGP leaks into the tumor stroma, activating GAMs and promoting tumor growth. Bevacizumab normalizes blood vessels, leading to PLVAP negativity and a reduction in GAM activity.
Techniques Used: Disruption, Activity Assay
Related Articles
Clinical Proteomics:Article Title: Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages Article Snippet: RT‐qPCR was performed using TaqMan polymerase with SYBR green fluorescence (Takara Bio) and an ABI PRISM 7300 sequence detector (Applied Biosystems, CA, USA). .. Sandwich ELISA:Article Title: Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages Article Snippet: RT‐qPCR was performed using TaqMan polymerase with SYBR green fluorescence (Takara Bio) and an ABI PRISM 7300 sequence detector (Applied Biosystems, CA, USA). .. Labeling:Article Title: Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages Article Snippet: RT‐qPCR was performed using TaqMan polymerase with SYBR green fluorescence (Takara Bio) and an ABI PRISM 7300 sequence detector (Applied Biosystems, CA, USA). .. |